Compositions and methods for improved protein production

Bodie, Elizabeth A.; Kim, Steve Sungjin

Title: Compositions and methods for improved protein production

Patent · Tue Jun 03 00:00:00 EDT 2014

OSTI ID:1133651

Bodie, Elizabeth A.; Kim, Steve Sungjin

The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.

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Research Organization:: National Renewable Energy Laboratory (NREL), Golden, CO (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC36-99GO10337

Assignee:: Danisco US Inc. (Palo Alto, CA)

Patent Number(s):: 8,741,654

Application Number:: 13/494,889

OSTI ID:: 1133651

Country of Publication:: United States

Language:: English

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Protease deficient filamentous fungal cells and methods of use thereof Landowski, Christopher; Huuskonen, Anne; Saarinen, Juhani https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9567596 US Patent Document 9,567,596	patent	February 2017

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