Poly(ethylene oxide) functionalization

Pratt, Russell Clayton

Title: Poly(ethylene oxide) functionalization

Patent · Tue Apr 08 00:00:00 EDT 2014

OSTI ID:1129165

Pratt, Russell Clayton

A simple procedure is provided by which the hydroxyl termini of poly(ethylene oxide) can be appended with functional groups to a useful extent by reaction and precipitation. The polymer is dissolved in warmed toluene, treated with an excess of organic base and somewhat less of an excess of a reactive acylating reagent, reacted for several hours, then precipitated in isopropanol so that the product can be isolated as a solid, and salt byproducts are washed away. This procedure enables functionalization of the polymer while not requiring laborious purification steps such as solvent-solvent extraction or dialysis to remove undesirable side products.

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Research Organization:: Seeo, Inc., Hayward, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: OE0000223

Assignee:: Seeo, Inc. (Hayward, CA)

Patent Number(s):: 8,691,919

Application Number:: 13/251,246

OSTI ID:: 1129165

Resource Relation:: Patent File Date: 2011 Oct 01

Country of Publication:: United States

Language:: English

References (11)

Monofunctional polyethylene glycol aldehydes Rosen, Perry; Nho, Kwang https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6916962 US Patent Document 6,916,962	patent	July 2005
Functionalized isobutylene-polyene copolymers and derivatives thereof Kolp, Christopher J. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7067594 US Patent Document 7,067,594	patent	June 2006
Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation Bentley, Michael D.; Harris, J. Milton; Kozlowski, Antoni https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7642323 US Patent Document 7,642,323	patent	January 2010
Fabric care composition Carswell, Robert John; Cooper, James Bernard; Khoshdel, Ezat https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030195136 US Patent Application 10/401454; 20030195136	patent-application	October 2003
Segmented polymers and their conjugates Kozlowski, Antoni; Shen, Xiaoming; Bentley, Michael D. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040236015 US Patent Application 10/734858; 20040236015	patent-application	November 2004
Methods and reagents for surface functionalization Cicero, Ronald; Forman, Jonathan; Kernen, Peter https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20050233473 US Patent Application 10/980597; 20050233473	patent-application	October 2005
Organic Synthesis on Soluble Polymer Supports: Liquid-Phase Methodologies Gravert, Dennis J.; Janda, Kim D. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960064l	journal	April 1997
Solubilities of Quaternary Ammonium Salts in Certain Organic Solvents Hughes, Vincent L.; Vernon, Arthur A. The Journal of Physical Chemistry, Vol. 56, Issue 7, p. 927-928 https://doi.org/10.1021/j150499a026	journal	July 1952
Designing Macromolecules for Therapeutic Applications: Polyester DendrimerPoly(ethylene oxide) “Bow-Tie” Hybrids with Tunable Molecular Weight and Architecture Gillies, Elizabeth R.; Fréchet, Jean M. J. Journal of the American Chemical Society, Vol. 124, Issue 47 https://doi.org/10.1021/ja028100n	journal	November 2002
Toward an Easy Access to Dendrimer-like Poly(ethylene oxide)s Feng, Xiao-Shuang; Taton, Daniel; Chaikof, Elliot L. Journal of the American Chemical Society, Vol. 127, Issue 31 https://doi.org/10.1021/ja0509432	journal	August 2005
Chemical Modification of Surface Active Poly(ethylene oxide)−Poly(propylene oxide) Triblock Copolymers Li, Jenq-Thun; Carlsson, Jan; Lin, Jinn-Nan Bioconjugate Chemistry, Vol. 7, Issue 5 https://doi.org/10.1021/bc960048v	journal	January 1996

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