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Title: High molecular weight polysaccharide that binds and inhibits virus

Patent ·
OSTI ID:1117665

This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods on inhibiting viral infectivity and/or pathogenicity, as well as immunogenic compositions. The invention further methods of inhibiting the growth of cancer cells and of ameliorating a symptom of aging. Additionally, the invention provides methods of detecting and/or quantifying and/or isolating viruses.

Research Organization:
World Force Technologies, LLC, Newport, OR, USA
Sponsoring Organization:
USDOE
DOE Contract Number:
FG09-93ER20097
Assignee:
World Force Technologies, LLC (Newport, OR)
Patent Number(s):
8,629,121
Application Number:
12/694,226
OSTI ID:
1117665
Resource Relation:
Patent File Date: 2010 Jan 26
Country of Publication:
United States
Language:
English

References (12)

Acidic polysaccharide CH-1 isolated from Chlorella pyrenoidosa and the use thereof patent August 1985
Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof patent October 1987
Proanthocyanidin polymers having antiviral activity and methods of obtaining same patent May 1993
Process for preparing grapeseed extracts enriched in procyanidol oligomers patent January 1996
Antiviral polysaccharide patent December 1996
Immunogenic polypeptides that mimic a surface polysaccharide antigen of a pathogenic microorganism, method for obtaining the same, and their use in vaccine compositions patent March 2003
Modified polysaccharide adjuvant-protein antigen conjugates, the preparation thereof and the use thereof patent June 2003
High molecular weight polysaccharide fraction from aloe vera with immunostimulatory activity patent-application February 2004
Lipid-regulating agent and use thereof patent-application December 2006
Carbohydrate analysis by high-performance anion-exchange chromatography with pulsed amperometric detection: The potential is still growing journal December 2000
Grape Seed Extract Activates Th1 Cells In Vitro journal March 2002
Antiviral property and mechanisms of a sulphated polysaccharide from the brown alga Sargassum patens against Herpes simplex virus type 1 journal November 2006

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60 APPLIED LIFE SCIENCES