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Title: Aerosol mass spectrometry systems and methods

Patent ·
OSTI ID:1093251

A system according to one embodiment includes a particle accelerator that directs a succession of polydisperse aerosol particles along a predetermined particle path; multiple tracking lasers for generating beams of light across the particle path; an optical detector positioned adjacent the particle path for detecting impingement of the beams of light on individual particles; a desorption laser for generating a beam of desorbing light across the particle path about coaxial with a beam of light produced by one of the tracking lasers; and a controller, responsive to detection of a signal produced by the optical detector, that controls the desorption laser to generate the beam of desorbing light. Additional systems and methods are also disclosed.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Number(s):
8,513,598
Application Number:
12/338,623
OSTI ID:
1093251
Country of Publication:
United States
Language:
English

References (12)

Aerodynamic Particle Sizing versus Light Scattering Intensity Measurement as Methods for Real-Time Particle Sizing Coupled with Time-of-Flight Mass Spectrometry journal January 1996
Real-Time Analysis of Individual Atmospheric Aerosol Particles:  Design and Performance of a Portable ATOFMS journal October 1997
Real-time detection method and system for identifying individual aerosol particles patent August 2007
Portable analyzer for determining size and chemical composition of an aerosol patent December 1999
MALDI-IM-ortho-TOF mass spectrometry with simultaneous positive and negative mode detection patent January 2007
On-line single-particle analysis by laser desorption mass spectrometry journal September 1991
Method and apparatus for determining the size and chemical composition of aerosol particles patent October 1997
Laser Ionization Mass Spectroscopy of Single Aerosol Particles journal January 1995
Real-time characterization of individual aerosol particles using time-of-flight mass spectrometry journal April 1994
Method and device for detecting and identifying bio-aerosol particles in the air patent October 2004
Reagentless Detection and Classification of Individual Bioaerosol Particles in Seconds journal January 2004
Devices and methods for the detection of particles patent January 2005

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