skip to main content

Title: Identification of M-CSF agonists and antagonists

The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.
Authors:
 [1] ;  [2] ;  [3] ;  [4] ;  [5] ;  [6] ;  [6] ;  [7] ;  [8]
  1. Mystic, CT
  2. Walnut Creek, CA
  3. Moraga, CA
  4. El Cerrito, CA
  5. San Rafael, CA
  6. Oakland, CA
  7. Martinez, CA
  8. Armonk, NY
Publication Date:
OSTI Identifier:
982807
Report Number(s):
6,025,146
US patent application 08/462,069
DOE Contract Number:
AC03-76SF00098
Resource Type:
Patent
Research Org:
UNIVERSITY OF CALIFORNIA
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES