Unravelling Microbial Communities with DNA-Microarrays: Challengesand Future Directions.

Journal Article · Thu Mar 08 00:00:00 EST 2007 · Microbial Ecology

DOI:https://doi.org/10.1007/s00248-006-9197-7· OSTI ID:926477

Wagner, Michael; Smidt, Hauke; Loy, Alexander; Zhou, Jizhong

High-throughput technologies are urgently needed formonitoring the formidable biodiversity and functional capabilities ofmicroorganisms in the environment. Ten years ago, DNA microarrays,miniaturized platforms for highly parallel hybridization reactions, foundtheir way into environmental microbiology and raised great expectationsamong researchers in the field. In this article, we briefly summarize thestate-of-the-art of microarray approaches in microbial ecology researchand discuss in more detail crucial problems and promising solutions.Finally, we outline scenarios for an innovative combination ofmicroarrays with other molecular tools for structure-function analysis ofcomplex microbial communities.

• Research Organization: COLLABORATION - U.Vienna/Austria
• DOE Contract Number: DE-AC02-05CH11231
• OSTI ID: 926477
• Report Number(s): LBNL-60302; R&D Project: VGTLJK; BnR: KP1501021
• Journal Information: Microbial Ecology, Vol. 53, Issue 3; Related Information: Journal Publication Date: Mar 8, 2007
• Country of Publication: United States
• Language: English

Related Subjects

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microarrays