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Title: Computer programs for multilocus haplotyping of general pedigrees

Journal Article · · American Journal of Human Genetics
OSTI ID:91201
;  [1];  [2]
  1. Univ. of Pittsburgh, PA (United States)
  2. Univ. of California, Los Angeles, CA (United States); and others

We have recently developed and implemented three different computer algorithms for accurate haplotyping with large numbers of codominant markers. Each of these algorithms employs likelihood criteria that correctly incorporate all intermarker recombination fractions. The three programs, HAPLO, SIMCROSS, and SIMWALK, are now available for haplotying general pedigrees. The HAPLO program will be distributed as part of the Programs for Pedigree Analysis package by Kenneth Lange. The SIMCROSS and SIMWALK programs are available by anonymous ftp from watson.hgen.pitt.edu. Each program is written in FORTRAN 77 and is distributed as source code. 15 refs.

OSTI ID:
91201
Journal Information:
American Journal of Human Genetics, Vol. 56, Issue 6; Other Information: PBD: Jun 1995
Country of Publication:
United States
Language:
English