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Title: United States Transuranium and Uranium Registries. Annual Report, October 1, 1993--September 30, 1994

This report summarizes the salient activities and progress of the United States Transuranium. and Uranium Registries for the period October 1, 1993 through September 30, 1994, along with details of specific programs areas including the National Human Radiobiology Tissue Repository (NHRTR) and tissue radiochemistry analysis project. Responsibility for tissue radioanalysis was transferred from Los Alamos National Laboratory to Washington State University in February 1994. The University of Washington was selected as the Quality Assurance/Quality Control laboratory and a three way intercomparison with them and LANL has been initiated. The results of the initial alpha spectrometry intercomparison showed excellent agreement among the laboratories and are documented in full in the Appendices to the report. The NHRTR serves as the initial point of receipt for samples received from participants in the USTUR program. Samples are weighed, divided, and reweighed, and a portion retained by the NHRTR as backup or for use in other studies. Tissue specimens retained in the NHRTR are maintained frozen at -70 C and include not only those from USTUR registrants but also those from the radium dial painter and thorium worker studies formerly conducted by Argonne National Laboratory. In addition, there are fixed tissues and a large collectionmore » of histopathology slides from all the studies, plus about 20,000 individual solutions derived from donated tissues. These tissues and tissue related materials are made available to other investigators for legitimate research purposes. Ratios of the concentration of actinides in various tissues have been used to evaluate the biokinetics, and retention half times of plutonium and americium. Retention half times for plutonium in various soft tissues range from 10-20 y except for the testes for which a retention half time of 58 y was observed. For americium, the retention half time in various soft tissues studied was 2.2-3.5 y.« less
Authors:
;  [1]
  1. comps. [eds.
Publication Date:
OSTI Identifier:
90696
Report Number(s):
USTUR--0036-95
ON: DE95016160; NC: NONE; TRN: 95:017907
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: [1995]
Research Org:
United States Transuranium and Uranium Registry, Richland, WA (United States)
Sponsoring Org:
Washington State Univ., Pullman, WA (United States)
Country of Publication:
United States
Language:
English
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; ACTINIDES; TISSUE DISTRIBUTION; RADIOCHEMICAL ANALYSIS; RADIOCHEMISTRY; QUALITY ASSURANCE; QUALITY CONTROL; PROGRESS REPORT; RADIOBIOLOGY; URANIUM; THORIUM; RADIUM; PLUTONIUM; LANL; AMERICIUM; RADIONUCLIDE KINETICS; BIOLOGICAL HALF-LIFE