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Title: Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use

The present invention provides a water-soluble luminescent quantum dot, a biomolecular conjugate thereof and a composition comprising such a quantum dot or conjugate. Additionally, the present invention provides a method of obtaining a luminescent quantum dot, a method of making a biomolecular conjugate thereof, and methods of using a biomolecular conjugate for ultrasensitive nonisotopic detection in vitro and in vivo.
Authors:
 [1] ;  [1] ;  [2]
  1. (Bloomington, IN)
  2. (Los Alamos, NM)
Publication Date:
OSTI Identifier:
874824
Report Number(s):
US 6468808
DOE Contract Number:
FG02-98ER14873
Resource Type:
Patent
Research Org:
INDIANA UNIVERSITY
Country of Publication:
United States
Language:
English
Subject:
water-soluble; luminescent; quantum; dots; biomolecular; conjugates; related; compositions; method; provides; water-soluble; luminescent; quantum; dot; biomolecular; conjugate; composition; comprising; quantum; dot; conjugate; additionally; provides; method; obtaining; luminescent; quantum; dot; method; biomolecular; conjugate; methods; biomolecular; conjugate; ultrasensitive; nonisotopic; detection; vitro; vivo /436/257/420/428/430/435/