Miniaturized flow injection analysis system
- Livermore, CA
A chemical analysis technique known as flow injection analysis, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38.times.25.times.3 mm, but can be designed for gas analysis and be substantially smaller in construction.
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- DOE Contract Number:
- W-7405-ENG-48
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Number(s):
- US 5644395
- OSTI ID:
- 871029
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
flow
injection
analysis
chemical
technique
quantities
reagents
sample
intermixed
reacted
capillary
reaction
products
detected
optically
electrochemically
means
highly
version
fabricated
utilizing
microfabrication
techniques
common
microelectronics
industry
microflow
capillaries
formed
etching
microchannels
silicon
glass
wafer
followed
bonding
commercially
available
microvalves
bonded
directly
channels
optical
absorption
detector
cell
near
outlet
light
delivered
collected
fiber
optics
designed
mainly
liquids
currently
measures
38
times
25
gas
substantially
construction
gas analysis
flow injection
optical absorption
chemical analysis
fiber optics
flow channels
flow channel
fiber optic
reaction product
reaction products
commercially available
fabrication techniques
absorption detector
chemical reagent
detector cell
injection analysis
analysis technique
cell formed
chemical reagents
capillary flow
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