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Title: Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

A method is disclosed for synthesizing peptides using water soluble enzyme polymer conjugates. The method comprises catalyzing the peptide synthesis with enzyme which has been covalently bonded to a polymer through at least three linkers which linkers have three or more hydroxyl groups. The enzyme is conjugated at lysines or arginines.
Authors:
 [1] ;  [2] ;  [3]
  1. (Columbus, OH)
  2. (Berkeley, CA)
  3. (St. Paul, MN)
Publication Date:
OSTI Identifier:
871005
Report Number(s):
US 5639633
DOE Contract Number:
AC03-76SF00098
Resource Type:
Patent
Research Org:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA
Country of Publication:
United States
Language:
English
Subject:
method; synthesizing; peptides; saccharide; linked; enzyme; polymer; conjugates; method; disclosed; synthesizing; peptides; water; soluble; enzyme; polymer; conjugates; method; comprises; catalyzing; peptide; synthesis; enzyme; covalently; bonded; polymer; linkers; linkers; hydroxyl; enzyme; conjugated; lysines; arginines; water soluble; method comprises; covalently bonded; polymer conjugates; polymer conjugates; method comprise; synthesizing peptides; synthesizing peptides; enzyme polymer; enzyme polymer /435/