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Title: Aminopropyl thiophene compounds

Radiopharmaceuticals useful in brain imaging comprising radiohalogenated thienylethylamine derivatives. The compounds are 5-halo-thiophene-2-isopropyl amines able to cross the blood-brain barrier and be retained for a sufficient length of time to allow the evaluation of regional blood flow by radioimaging of the brain.
 [1] ;  [2]
  1. (Knoxville, TN)
  2. (Oak Ridge, TN)
Publication Date:
OSTI Identifier:
Report Number(s):
US 4914215
Resource Type:
Research Org:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN
Country of Publication:
United States
aminopropyl; thiophene; compounds; radiopharmaceuticals; useful; brain; imaging; comprising; radiohalogenated; thienylethylamine; derivatives; 5-halo-thiophene-2-isopropyl; amines; blood-brain; barrier; retained; sufficient; length; time; allow; evaluation; regional; blood; flow; radioimaging; blood flow; sufficient length; radiohalogenated thienylethylamine; thienylethylamine derivatives; radiopharmaceuticals useful; comprising radiohalogenated; imaging comprising; brain imaging; blood-brain barrier; /999/