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Title: A physical map of the human genome

Journal Article · · Nature
DOI:https://doi.org/10.1038/35057157· OSTI ID:828552

The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.

Research Organization:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE Director. Office of Science. Office of Biological and Environmental Research (US)
DOE Contract Number:
AC03-76SF00098
OSTI ID:
828552
Report Number(s):
LBNL-47878; R&D Project: LGFGAA; TRN: US200427%%338
Journal Information:
Nature, Vol. 409; Other Information: Journal Publication Date: 02/15/2001; PBD: 1 Jan 2001
Country of Publication:
United States
Language:
English