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Title: Effect of heavy metals ions on enzyme activity in the Mediterranean mussel, Donax trunculus

Heavy metal ions strongly are bound by sulfhydryl groups of proteins. Sulfhydryl binding changes the structure and enzymatic activities of proteins and causes toxic effects evident at the whole organism level. Heavy metal ions like Cd, Cu, Hg, Zn, and Pb in sufficiently high concentrations might kill organisms or cause other adverse effects that changing aquatic community structures. Bivalves are known to be heavy metal accumulators. The aim of the present study was to examine the effects of different concentrations of each of five heavy metal ions on the activity of four enzymes in D. trunculus. As it is known that heavy metals inhibit the activity of a wide range of enzymes, the authors chose representative examples of dehydrogenases (lactate and malate dehydrogenases), respiratory enzyme (cytochrome oxidase) and digestive enzyme ({alpha}-amylase). The acute effects of different concentrations of selected metals were examined. These concentrations were higher than those found usually in the locality where the animals occur, but might be encountered during a given event of pollution.
Authors:
;  [1]
  1. (Bar Ilan Univ., Ramat-Gan (Israel))
Publication Date:
OSTI Identifier:
7244270
Resource Type:
Journal Article
Resource Relation:
Journal Name: Bulletin of Environmental Contamination and Toxicology; (USA); Journal Volume: 42:6
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; METALS; BIOLOGICAL EFFECTS; MUSSELS; ENZYME ACTIVITY; BIOCHEMISTRY; CYTOCHROME OXIDASE; DOSE-RESPONSE RELATIONSHIPS; IONS; LACTATE DEHYDROGENASE; MEDITERRANEAN SEA; PEPTIDE HYDROLASES; ANIMALS; AQUATIC ORGANISMS; CHARGED PARTICLES; CHEMISTRY; ELEMENTS; ENZYMES; HAEM DEHYDROGENASES; HEMIACETAL DEHYDROGENASES; HYDROLASES; INVERTEBRATES; MOLLUSCS; OXIDOREDUCTASES; SEAS; SURFACE WATERS 560300* -- Chemicals Metabolism & Toxicology