Reliability of single kidney glomerular filtration rate measured by a 99mTc-DTPA gamma camera technique
The reliability of a previously published method for determination of single kidney glomerular filtration rate (SKGFR) by means of technetium-99m-diethylenetriaminepenta-acetate (99mTc-DTPA) gamma camera renography was evaluated. The day-to-day variation in the calculated SKGFR values was earlier found to be 8.8%. The technique was compared to the simultaneously measured renal clearance of inulin in 19 unilaterally nephrectomized patients with GFR varying from 11 to 76 ml/min. The regression line (y = 1.04 X -2.5) did not differ significantly from the line of identity. The standard error of estimate was 4.3 ml/min. In 17 patients the inter- and intraobserver variation of the calculated SKGFR values was 1.2 ml/min and 1.3 ml/min, respectively. In 21 of 25 healthy subjects studied (age range 27-29 years), total GFR calculated from the renograms was within an established age-dependent normal range of GFR.
- Research Organization:
- Frederiksberg Hospital, Copenhagen, Denmark
- OSTI ID:
- 7188633
- Journal Information:
- Uremia Invest.; (United States), Vol. 2
- Country of Publication:
- United States
- Language:
- English
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DTPA
RENAL CLEARANCE
INULIN
KIDNEYS
RENOGRAPHY
TECHNETIUM 99
GAMMA CAMERAS
PATIENTS
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
CAMERAS
CARBOHYDRATES
CARBOXYLIC ACIDS
CHELATING AGENTS
CLEARANCE
DIAGNOSTIC TECHNIQUES
DRUGS
EXCRETION
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
POLYSACCHARIDES
RADIOISOTOPES
RADIOLOGY
RADIOPROTECTIVE SUBSTANCES
SACCHARIDES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics