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Title: Studies on prenatal and postnatal development in rats exposed to 60-Hz electric fields

A series of three experiments was performed to determine the effects of 30-day exposures to uniform 60-Hz electric fields (100 kV/m) on reproduction and on growth and development in the fetuses and offspring of rats. In the first experiment, exposure of females for 6 days prior to and during the mating period did not affect their reproductive performance, and continued exposure through 20 days of gestation (dg) did not affect the viability, size, or morphology of their fetuses. In the second experiment, exposure of the pregnant rat was begun on 0 dg and continued until the resulting offspring reached 8 days of age. In the third experiment, exposure began at 17 dg and continued through 25 days of postnatal life. In the second and third experiments, no statistically significant differences suggesting impairment of the growth or survival of exposed offspring were detected. In the second experiment, a significantly greater percentage of the exposed offspring showed movement, standing, and grooming at 14 days of age than among-sham-exposed offspring. There was a significant decrease at 14 days in the percentage of exposed offspring displaying the righting reflex in the second experiment and negative geotropism in the third experiment. These differences were allmore » transient and were not found when the animals were tested again at 21 days of age. Evaluation of the reproductive integrity of the offspring of the second experiment did not disclose any deficits.« less
Authors:
; ; ;
Publication Date:
OSTI Identifier:
7188374
Resource Type:
Journal Article
Resource Relation:
Journal Name: Bioelectromagnetics (N.Y.); (United States); Journal Volume: 5:1
Research Org:
Biology and Chemistry Department, Pacific Northwest Laboratory, Richland, Washington
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ELECTRIC FIELDS; BIOLOGICAL EFFECTS; FETUSES; GROWTH; HZ RANGE; PRENATAL EXPOSURE; RATS; REPRODUCTION; ANIMALS; FREQUENCY RANGE; MAMMALS; RODENTS; VERTEBRATES 560400* -- Other Environmental Pollutant Effects