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Title: A high-resolution linkage map of human 9q34. 1

Journal Article · · Genomics; (United States)
;  [1]; ; ;  [2]
  1. Brigham and Women's Hospital, Boston, MA (United States)
  2. Massachusetts General Hospital, Boston, MA (United States)

A map comprising 16 distinct markers with heterozygosities of 0.61-0.92 for a 10-cM region of human 9q34.1 is presented. The map incorporates four genes and has a maximum intermarker interval of 2.1 cM. Markers were analyzed in the Venezuelan reference pedigrees and all were placed uniquely in the map with a minimum likelihood of 676:1. The map should prove useful in analysis of families segregating dystonia and tuberous sclerosis, as the DYT1 and TSC1 loci map within this region. 18 refs., 2 figs., 2 tabs.

OSTI ID:
7160315
Journal Information:
Genomics; (United States), Vol. 17:3; ISSN 0888-7543
Country of Publication:
United States
Language:
English