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Title: Cellular and molecular pathways of extremely-low-frequency electromagnetic field interactions with living systems

There is growing evidence that environmental electric and magnetic fields in the extremely-low-frequency (ELF) band below 300 Hz can influence biological functions by mechanisms that are only poorly understood at the present time. The primary objectives of this paper are to review the physical properties of ELF fields, their interactions with living systems at the tissue, cellular, and subcellular levels, and the key role of cell membranes ;in the transduction of signals from imposed ELF fields. Topics of discussion include signal-to-noise ratios for single cells and cell aggregates, resonance phenomena involving a combination of static and ELF magnetic fields, and the possible influence of ELF fields on molecular signaling pathways that involve membrane receptors and cytoplasmic second messengers.
Authors:
Publication Date:
OSTI Identifier:
7107135
Report Number(s):
PNL-SA-20368; CONF-920630--1
ON: DE92019084
DOE Contract Number:
AC06-76RL01830
Resource Type:
Conference
Resource Relation:
Conference: 1. world congress for electricity and magnetism in biology and medicine, Orlando, FL (United States), 14-29 Jun 1992
Research Org:
Pacific Northwest Lab., Richland, WA (United States)
Sponsoring Org:
DOE; USDOE, Washington, DC (United States)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CELL MEMBRANES; FARADAY INDUCTION; LONG WAVE RADIATION; BIOLOGICAL EFFECTS; BIOELECTRICITY; ELECTROMAGNETIC FIELDS; PHOSPHOTRANSFERASES; POST-TRANSLATION MODIFICATION; CELL CONSTITUENTS; ELECTRICITY; ELECTROMAGNETIC RADIATION; ENZYMES; INDUCTION; MEMBRANES; ORGANIC COMPOUNDS; PHOSPHORUS-GROUP TRANSFERASES; PROTEINS; RADIATIONS; RADIOWAVE RADIATION; TRANSFERASES 560400* -- Other Environmental Pollutant Effects