Interaction between genes Mos and mwh expressed in somatic cells of Drosophila melanogaster

Journal Article · Sat Jul 01 00:00:00 EDT 1995 · Russian Journal of Genetics

OSTI ID:70455

Vaisman, N Ya; Zakharov, I K ^[1]

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1. Institute of Genetics and Cytology, Novosibirsk (Russian Federation)

Gene Mosaic (Mos) of chromosome 3 of Drosophila melanogaster was located by means of dominant markers Ly, Sb, and Dr. This gene was shown to be located between Ly and Sb in the centromeric region (45-50 map units). An analysis of interaction between Mos and mwh genes in cis- and trans-heterozygotes showed a significant effect of the Mos gene on mutability (recombinogenesis) of chromosome mwh in somatic cells. In the cis heterozygote mwh Mos/++, the frequency of small mutant clones on wings of flies increased. In mwh/Mos heterozygotes, the Mos gene caused a significant reduction of dorsocentral and scutellar bristles (78% in mwh/Mos, 85% in mwh +/+ Mos, and 98% in mwh Mos/mwh +). 20 refs., 3 tabs.

• OSTI ID: 70455
• Journal Information: Russian Journal of Genetics, Vol. 31, Issue 3; Other Information: PBD: 1995; TN: Translated from Genetika; 31: No. 3, 358-362(1995)
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
GENES
GENE MUTATIONS
DROSOPHILA
SOMATIC CELLS
CHROMOSOMES
MOSAICISM
GENETIC MAPPING
CENTROMERES
BIOLOGICAL MARKERS