Plasma beta-endorphin-like immunoreactivity and its variations in baboons

Journal Article · Tue Apr 01 00:00:00 EST 1986 · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)

OSTI ID:7025018

Golanov, E V; Fufacheva, A A; Parin, S B

This paper determines the level of beta-endorphin-like immunoreactivity (beta-elir) in the blood plasma of baboons and studies its changes in certain situations. For radioimmunoassay of beta-ELIR in the blood plasma, a standard kit and the appropriate technique were used. The background plasma beta-ELIR level of the baboons, in a state of quiet wakefulness, was 0.0 = 1.0 fmoles/ml. The total level of b-ELIR was 134 plus or minus 24 pg/ml. The data show that elevation of the plasma b-ELIR level accompanies stress formation, including the development of a state of shock in baboons. A definite role in the regulation of the plasma b-endorphin level may be played by the paraventricular-perifornical region of the hypothalamus.

• Research Organization: A.L. Myasnikov Institute of Clinical Cardiology Acad. of Med Sci., Sukhumi
• OSTI ID: 7025018
• Journal Information: Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Vol. 100:12
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
APES
BIOLOGICAL STRESS
IMMUNE REACTIONS
BLOOD PLASMA
RADIOIMMUNOASSAY
ENDORPHINS
BIOLOGICAL EFFECTS
BIOLOGICAL SHOCK
HYPOTHALAMUS
LIPOTROPIC FACTORS
PITUITARY GLAND
QUANTITY RATIO
ANIMALS
AUTONOMIC NERVOUS SYSTEM AGENTS
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
BRAIN
CENTRAL NERVOUS SYSTEM
DRUGS
ENDOCRINE GLANDS
GLANDS
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
MAMMALS
MATERIALS
NERVOUS SYSTEM
NEUROREGULATORS
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
RADIOASSAY
RADIOIMMUNOLOGY
TRACER TECHNIQUES
VERTEBRATES
550201* - Biochemistry- Tracer Techniques