Asbestos bodies in children's lungs. An association with sudden infant death syndrome and bronchopulmonary dysplasia
Lungs from 46 autopsied children (age range, 1 to 27 months) were examined for asbestos bodies using a bleach-digestion extraction technique. Ten (21.7%) of 46 children had asbestos bodies in their lungs. Of these ten children, seven were diagnosed with sudden infant death syndrome, and three were diagnosed with bronchopulmonary dysplasia. Thus, 46.6% of children with sudden infant death syndrome and 42.8% of children with bronchopulmonary dysplasia had asbestos bodies. Impaired lung-clearing mechanisms due to either abnormal lung physiology or reorganization of pulmonary architecture may be significant in the formation of asbestos bodies. Additionally, children with asbestos bodies may have been exposed to higher ambient levels of asbestos and other pollutants.
- Research Organization:
- Univ. Texas Medical Branch, Galveston (USA)
- OSTI ID:
- 7024772
- Journal Information:
- Arch. Pathol.; (United States), Vol. 112:5
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ASBESTOS
LUNG CLEARANCE
TOXICITY
CHILDREN
SENSITIVITY
AIR POLLUTION
AUTOPSY
DEATH
ENVIRONMENTAL EXPOSURE
INHIBITION
LUNGS
AGE GROUPS
BODY
CLEARANCE
DIAGNOSTIC TECHNIQUES
EXCRETION
ORGANS
POLLUTION
RESPIRATORY SYSTEM
560300* - Chemicals Metabolism & Toxicology