Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats

Smith, J C; Failla, M L; Fields, M; Revett, K R; Rose, A

Title: Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats

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Abstract

Dietary fructose, when compared to cornstarch, exacerbates copper deficiency. The purpose of this study was to determine whether Zn deficiency is similarly enhanced by high fructose intake. Seventy-five male SD rats were randomly assigned to one of the following diets containing 62% of the indicated carbohydrate: Zn deficient (0.6 ppm) X fructose; Zn deficient X starch; Zn supplemented (32 ppm) X fructose; Zn supplemented X starch. Animals were pair-fed to the Zn deficient X fructose group for 4 weeks. Survival, weight gain and tissue weight were also affected by dietary Zn, but not dietary carbohydrate. Dietary carbohydrate also failed to alter food intake of rats consuming Zn deficient diets. Unlike copper deficiency, the severity of Zn deficiency is not increased by feeding diets high in fructose compared to starch. The lack of a carbohydrate effect on zinc status indicates that the fructose-copper interaction is selective. This knowledge will facilitate the design of studies aimed at defining the mechanism(s) underlying fructose-trace element interaction.

Authors:: Smith, J C; Failla, M L; Fields, M; Revett, K R; Rose, A

Publication Date:: Wed Mar 05 00:00:00 EST 1986

Research Org.:: Dept. of Agriculture, Beltsville, MD

OSTI Identifier:: 7024476

Report Number(s):: CONF-8604222-
Journal ID: CODEN: FEPRA

Resource Type:: Journal Article

Journal Name:: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)

Additional Journal Information:: Journal Volume: 45:4; Conference: 70. annual meeting of the Federation of American Society for Experimental Biology, St. Louis, MO, USA, 13 Apr 1986

Country of Publication:: United States

Language:: English

Subject:: 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; FRUCTOSE; BIOCHEMICAL REACTION KINETICS; ZINC; NUTRITIONAL DEFICIENCY; DIET; INTAKE; RATS; STARCH; WEIGHT; ANIMALS; CARBOHYDRATES; ELEMENTS; HEXOSES; KETONES; KINETICS; MAMMALS; METALS; MONOSACCHARIDES; ORGANIC COMPOUNDS; POLYSACCHARIDES; REACTION KINETICS; REAGENTS; RODENTS; SACCHARIDES; VERTEBRATES; 560300* - Chemicals Metabolism & Toxicology

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                    Smith, J C, Failla, M L, Fields, M, Revett, K R, and Rose, A. Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats.  United States: N. p., 1986. 
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                    Smith, J C, Failla, M L, Fields, M, Revett, K R, & Rose, A. Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats.  United States.

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                    Smith, J C, Failla, M L, Fields, M, Revett, K R, and Rose, A. 1986.  
        "Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats".  United States.

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@article{osti_7024476,

  title        = {Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats},

  author       = {Smith, J C and Failla, M L and Fields, M and Revett, K R and Rose, A},

  abstractNote = {Dietary fructose, when compared to cornstarch, exacerbates copper deficiency. The purpose of this study was to determine whether Zn deficiency is similarly enhanced by high fructose intake. Seventy-five male SD rats were randomly assigned to one of the following diets containing 62% of the indicated carbohydrate: Zn deficient (0.6 ppm) X fructose; Zn deficient X starch; Zn supplemented (32 ppm) X fructose; Zn supplemented X starch. Animals were pair-fed to the Zn deficient X fructose group for 4 weeks. Survival, weight gain and tissue weight were also affected by dietary Zn, but not dietary carbohydrate. Dietary carbohydrate also failed to alter food intake of rats consuming Zn deficient diets. Unlike copper deficiency, the severity of Zn deficiency is not increased by feeding diets high in fructose compared to starch. The lack of a carbohydrate effect on zinc status indicates that the fructose-copper interaction is selective. This knowledge will facilitate the design of studies aimed at defining the mechanism(s) underlying fructose-trace element interaction.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/7024476},
  journal      = {Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)},
number       = ,

  volume       = 45:4,

  place        = {United States},

  year         = {Wed Mar 05 00:00:00 EST 1986},

  month        = {Wed Mar 05 00:00:00 EST 1986}

}

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