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Title: Identification of a group of Haemophilus influenzae penicillin-binding proteins that may have complementary physiological roles

Journal Article · · Antimicrobial Agents and Chemotherapy; (USA)
DOI:https://doi.org/10.1128/AAC.34.2.363· OSTI ID:7009586
; ;  [1]
  1. Eli Lilly Company, Indianapolis, IN (USA)

(35S)penicillin bound to different Haemophilus influenzae proteins in assays performed at 20, 37, or 42{degrees}C. Penicillin-binding proteins 3a, 3b, 4, and 4' formed a group characterized by their affinity for moxalactam, cefotaxime, and piperacillin. Penicillin-binding protein 4' showed specific properties that may reflect its complementary role in septation.

OSTI ID:
7009586
Journal Information:
Antimicrobial Agents and Chemotherapy; (USA), Vol. 34:2; ISSN 0066-4804
Country of Publication:
United States
Language:
English