Cyclic voltammetry at TCNQ and TTF-TCNQ modified platinum electrodes: A study of the glucose oxidase/glucose and galactose oxidase/galactose systems
Recent work has shown that the synthetic metal TTF-TCNQ can be used as an electrode material for the oxidation of enzymes containing the prosthetic group flavin adenine dinucleotide (FAD). This direct electron transfer (direct in the sense that oxygen is not a mediator) between reduced enzyme and electrode, a process which does not occur to any measurable extent at a typical metal electrode, is not very well understood. In the present work, electron transfer between reduced glucose oxidase and TTF-TCNQ is investigated using cyclic voltammetry, and it is also shown that TCNQ itself can mediate this electron transfer between the enzyme and a platinum electrode. In addition to the glucose oxidase studies, cyclic voltammetric experiments have been performed on the galactose oxidase system, which contains a copper redox center rather than FAD. The results of these experiments demonstrate that the catalytic ability of TTF-TCNQ in enzyme-based electrochemical sensors is quite general. 15 refs., 4 figs.
- Research Organization:
- Brookhaven National Lab., Upton, NY (USA)
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 7005905
- Report Number(s):
- BNL-41558; CONF-880669-13; ON: DE88015820
- Resource Relation:
- Conference: International conference on science and technology of synthetic metals, Santa Fe, NM, USA, 26 Jun 1988; Other Information: Portions of this document are illegible in microfiche products
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ENZYMES
OXIDATION
PLATINUM
CATALYTIC EFFECTS
TTF-TCNQ
CHEMICAL REACTION KINETICS
ELECTROCATALYSTS
ELECTRODES
ELECTRON TRANSFER
GALACTOSE
GLUCOSE
POTENTIOSTATS
VOLTAMETRY
ALDEHYDES
CARBOHYDRATES
CATALYSTS
CHEMICAL REACTIONS
ELEMENTS
HETEROCYCLIC COMPOUNDS
HEXOSES
KINETICS
MEASURING INSTRUMENTS
METALS
MONOSACCHARIDES
NITRILES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PLATINUM METALS
REACTION KINETICS
SACCHARIDES
TRANSITION ELEMENTS
400400* - Electrochemistry
400201 - Chemical & Physicochemical Properties