(51Cr)EDTA intestinal permeability in children with cow's milk intolerance

Journal Article · Thu Feb 01 00:00:00 EST 1990 · Journal of Pediatric Gastroenterology and Nutrition; (USA)

DOI:https://doi.org/10.1097/00005176-199002000-00008· OSTI ID:6993222

Schrander, J J; Unsalan-Hooyen, R W; Forget, P P; Jansen, J ^[1]

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1. Academic Hospital Maastricht (Netherlands)

Making use of ({sup 51}Cr)EDTA as a permeability marker, we measured intestinal permeability in a group of 20 children with proven cow's milk intolerance (CMI), a group of 17 children with similar complaints where CMI was excluded (sick controls), and a group of 12 control children. ({sup 51}Cr)EDTA test results (mean +/- SD) were 6.85 +/- 3.64%, 3.42 +/- 0.94%, and 2.61 +/- 0.67% in the group with CMI, the sick control, and the control group, respectively. When compared to both control groups, patients with cow's milk intolerance (CMI) showed a significantly increased small bowel permeability. We conclude that the ({sup 51}Cr)EDTA test can be helpful for the diagnosis of cow's milk intolerance.

• OSTI ID: 6993222
• Journal Information: Journal of Pediatric Gastroenterology and Nutrition; (USA), Vol. 10:2; ISSN 0277-2116
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
LACTOSE
SENSITIVITY
SMALL INTESTINE
PERMEABILITY
CHROMIUM 51
EDTA
MILK
PATHOGENESIS
TRACER TECHNIQUES
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CARBOHYDRATES
CARBOXYLIC ACIDS
CHELATING AGENTS
CHROMIUM ISOTOPES
DIGESTIVE SYSTEM
DISACCHARIDES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
FOOD
GASTROINTESTINAL TRACT
INTERMEDIATE MASS NUCLEI
INTESTINES
ISOTOPE APPLICATIONS
ISOTOPES
MATERIALS
NUCLEI
OLIGOSACCHARIDES
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPES
SACCHARIDES
550901* - Pathology- Tracer Techniques