Myocardial performance and perfusion during exercise in patients with coronary artery disease caused by Kawasaki disease

Journal Article · Mon Jan 01 00:00:00 EST 1990 · Journal of Pediatrics; (USA)

DOI:https://doi.org/10.1016/S0022-3476(05)81644-0· OSTI ID:6983758

Paridon, S M; Ross, R D; Kuhns, L R; Pinsky, W W ^[1]

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1. Wayne State Univ. School of Medicine, Detroit (USA)

For a study of the natural history of coronary artery lesions after Kawasaki disease and their effect on myocardial blood flow reserve with exercise, five such patients underwent exercise testing on a bicycle. Oxygen consumption, carbon dioxide production, minute ventilation, and electrocardiograms were monitored continuously. Thallium-201 scintigraphy was performed for all patients. One patient stopped exercise before exhaustion of cardiovascular reserve but had no evidence of myocardial perfusion abnormalities. Four patients terminated exercise because of exhaustion of cardiovascular reserve; one had normal cardiovascular reserve and thallium scintiscans, but the remaining patients had diminished cardiovascular reserve. Thallium scintigrams showed myocardial ischemia in two and infarction in one. No patient had exercise-induced electrocardiographic changes. These results indicate that patients with residual coronary artery lesions after Kawasaki disease frequently have reduced cardiovascular reserve during exercise. The addition of thallium scintigraphy and metabolic measurements to exercise testing improved the detection of exercise-induced abnormalities of myocardial perfusion.

• OSTI ID: 6983758
• Journal Information: Journal of Pediatrics; (USA), Vol. 116:1; ISSN 0022-3476
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARDIOVASCULAR DISEASES
DIAGNOSIS
HEART
SCINTISCANNING
MYOCARDIUM
BLOOD FLOW
ELECTROCARDIOGRAMS
EXERCISE
PATIENTS
RESPIRATION
THALLIUM 201
BETA DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
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DISEASES
ELECTRON CAPTURE RADIOISOTOPES
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ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MUSCLES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
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