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Title: Stress scintigraphy using single-photon emission computed tomography in the evaluation of coronary artery disease

Twenty-seven patients with angina pectoris, 24 with postmyocardial infarction angina and 7 with normal coronary arteries were examined by exercise thallium-201 emission computed tomography (SPECT) and planar scintigraphy. Exercise SPECT was compared with the reperfusion imaging obtained approximately 2 to 3 hours after exercise. The sensitivity and specificity of demonstrating involved coronary arteries by identifying the locations of myocardial perfusion defects were 96 and 87% for right coronary artery, 88 and 89% for left anterior descending artery (LAD) and 78 and 100% for left circumflex artery (LC). These figures are higher than those for planar scintigraphy (85 and 87% for right coronary artery, 73 and 89% for LAD and 39 and 100% for LC arteries). In patients with 3-vessel disease, sensitivity of SPECT (100, 88 and 75% for right coronary artery, LAD and LC, respectively) was higher than planar imaging (88, 63 and 31%, respectively), with a significant difference for LC (p less than 0.05). In 1, 2 and 0-vessel disease the sensitivity and specificity of the 2 techniques were comparable. Multivessel disease was more easily identified as multiple coronary involvement than planar imaging with a significant difference in 3-vessel disease (p less than 0.05). In conclusion, stress SPECT providesmore » useful information for the identification of LC lesions in coronary heart disease, including 3-vessel involvement.« less
Authors:
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Publication Date:
OSTI Identifier:
6975037
Resource Type:
Journal Article
Resource Relation:
Journal Name: Am. J. Cardiol.; (United States); Journal Volume: 53:9
Research Org:
Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CORONARIES; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; EXERCISE; MYOCARDIAL INFARCTION; PATIENTS; THALLIUM ISOTOPES; ARTERIES; BLOOD VESSELS; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; DISEASES; EMISSION COMPUTED TOMOGRAPHY; ISOTOPES; ORGANS; TOMOGRAPHY 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics