Development of a toxin knowledge system. Final summary report 6 April 1987-1 December 1989

Technical Report · Mon Nov 12 00:00:00 EST 1990

OSTI ID:6954751

Trammel, H L

The development of a Toxin Knowledge System (TKS) was begun in an attempt to meet the needs for readily accessible toxin knowledge. This system was designed to extract facts from published literature using structured abstracting techniques, store these facts in a standard knowledge structure, control the terminology entered through the use of a standard nomenclature system, and subsequently generate standard monographs on individual toxins. The system uses a relational database management system and associated programming language on a microcomputer. Standard nomenclature systems were created for clinical findings, journal abbreviations, study terminology, and book information. The development of a chemical vocabulary was unsuccessful. The current TKS version is of primary value with papers describing in vivo toxicology studies. The TKS application facilitates the extraction of needed information from both journals and books through a sophisticated user interface. The user enters citation data and is then prompted for information about each study design (up to 99 per paper), each subject group (up to 99 per design) and exposure regimen (up to 99 per design) within each design, and how these factors interact to produce clinical effects.

• Research Organization: Illinois Univ., Urbana, IL (United States). Coll. of Veterinary Medicine
• OSTI ID: 6954751
• Report Number(s): AD-B-152646/6/XAB; CNN: DAMD17-87-C-7114
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
TOXICITY
INFORMATION RETRIEVAL
KNOWLEDGE BASE
PROGRESS REPORT
DOCUMENT TYPES
560300* - Chemicals Metabolism & Toxicology
990301 - Information Handling- Data Handling- (1992-)