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Title: Riboflavin production during growth of Micrococcus luteus on pyridine

Micrococcus luteus produced 29 {mu}M riboflavin during growth on 6.5 mM pyridine but not during growth on other substrates. On the basic of the results of radiolabelling studies, riboflavin was not directly synthesized from pyridine. Pyridine may interfere with riboflavin biosynthesis or elicit a general stress response in M. luteus. The optimum concentration of pyridine for both growth of the organism and pyridine degradation was 13 mM. Above 25 mM, pyridine temporarily inhibited growth, pyridine degradation, oxygen uptake, and pigment production.
Authors:
 [1] ;  [2]
  1. (Environmental Chemistry Lab., Dow Elanco, Midland, MI (United States))
  2. (Ohio State Univ., Columbus (United States))
Publication Date:
OSTI Identifier:
6952148
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied and Environmental Microbiology; (United States); Journal Volume: 58:10
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 54 ENVIRONMENTAL SCIENCES; MICROCOCCUS; METABOLISM; PYRIDINES; RIBOFLAVIN; BIOSYNTHESIS; BIOLOGICAL STRESS; GROWTH; TOXICITY; AZINES; BACTERIA; HETEROCYCLIC COMPOUNDS; MICROORGANISMS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; SYNTHESIS; VITAMIN B GROUP; VITAMINS 560300* -- Chemicals Metabolism & Toxicology; 540210 -- Environment, Terrestrial-- Basic Studies-- (1990-)