Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism

Journal Article · Fri Apr 01 00:00:00 EST 1988 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198804000-00006· OSTI ID:6922505

Ling, M C; Dake, M D; Okerlund, M D

Amiodarone is an iodinated antiarrhythmic agent that is effective in the treatment of atrial and ventricular arrhythmias. A number of side effects are seen, including pulmonary toxicity and thyroid dysfunction. A patient with both amiodarone-induced pneumonitis and hyperthyroidism who exhibited abnormal gallium activity in the lungs, as well as diffuse gallium uptake in the thyroid gland is presented. The latter has not been previously reported and supports the concept of iodide-induced thyroiditis with gallium uptake reflecting the inflammatory response.

• Research Organization: Univ. of California, San Francisco (USA)
• OSTI ID: 6922505
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 13:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GALLIUM ISOTOPES
UPTAKE
LUNGS
RADIONUCLIDE KINETICS
THYROID
HYPERTHYROIDISM
PNEUMONIA
BODY
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
ISOTOPES
ORGANS
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man