Aqueous metallic factors and cancer mortality
The purpose of this study was to investigate the possible relationships between aqueous metals and cancer mortality in the upper Colorado River Basin in the State of Colorado for the period 1970-1980. All death certificates for the State of Colorado for the study period were examined for cause of death, and a magnetic tape containing abstracts of certificates for all cancer mortality was produced by the Vital Statistics Division of the Colorado Department of Health. Decedents were grouped by county, sex, and type of cancer and all records for cancers of the digestive organs, genital organs, and urinary organs were categorized by county and sex. Standardized cause- and sex-specific mortality ratios were calculated for each year for each of the fourteen counties in the Colorado Basin and were used as the dependent variables in subsequent analyses. Aqueous metals data were obtained from the Environmental Protection Agency master data base for the area and period and were factor analyzed to establish objective groups of metals which were present in the waters of the Basin. Metals included in the study were As, Be, Cd, Cu, Cr, Fe, Pb, Mn, Hg, Ni, Se, and Zn. The correlation matrix was factor analyzed and five common factors were extracted by promax rotation. The set of Mn, Zn, Cu, Fe, and Pb was found to relate to cancer mortality in each sex. Further independent analyses for each sex. Further independent analyses for each sex indicated that Mn was most directly related to cancer mortality for both sexes, and that Zn was most inversely related to cancer mortality for both sexes.
- Research Organization:
- Colorado Univ., Boulder, CO (USA)
- OSTI ID:
- 6905181
- Resource Relation:
- Other Information: Thesis (Ph. D.)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
METALS
BIOLOGICAL EFFECTS
MORTALITY
EPIDEMIOLOGY
ARSENIC COMPOUNDS
CADMIUM COMPOUNDS
COLORADO
COPPER COMPOUNDS
HUMAN POPULATIONS
IRON COMPOUNDS
LEAD COMPOUNDS
MANGANESE
NICKEL COMPOUNDS
RIVERS
SELENIUM COMPOUNDS
SEX DEPENDENCE
STATISTICS
US EPA
ZINC COMPOUNDS
ELEMENTS
FEDERAL REGION VIII
MATHEMATICS
NATIONAL ORGANIZATIONS
NORTH AMERICA
POPULATIONS
STREAMS
SURFACE WATERS
TRANSITION ELEMENT COMPOUNDS
TRANSITION ELEMENTS
US ORGANIZATIONS
USA
560300* - Chemicals Metabolism & Toxicology