Relationship between dietary copper intake and indices of copper status in men, premenopausal and postmenopausal women
- Univ. of Maryland, College Park (USA)
Dietary copper (Cu) intake, red blood cell superoxide dismutase (SOD), ceruloplasmin (Cp) and plasma Cu were determined in 18 men, 18 premenopausal (PRE) and 18 postmenopausal (POST) women. Follicle stimulating hormone and leutinizing hormone were measured to verify menopausal status in women. SOD levels were significantly different in men, PRE and POST women and were used to divide subjects into adequate (350-700 U/mI) and inadequate (<350 U/ml) Cu status. Dietary Cu intake including supplements was highest for men (2.53 mg/day) as compared to PRE (1.35 mg/day) and POST (1.86 mg/day) women. There was an inverse correlation between dietary Cu intake and SOD levels. Plasma Cu levels were significantly higher in women (102.8 {mu}g/dl PRE, 108.95 POST {mu}g/dl) compared to men (88.34 {mu}g/dl). Cp levels showed a positive correlation with plasma Cu but did not show a sex effect. The present Cu intake levels were calculated from diet records using a food Cu data base. These results are in the process of being verified by direct analysis of Cu level in a 3 day food composite. The results indicate that Cu intake alone is not a good predictor of Cu status as determine by SOD levels.
- OSTI ID:
- 6896736
- Journal Information:
- FASEB Journal (Federation of American Societies for Experimental Biology); (USA), Vol. 3:3; ISSN 0892-6638
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
COPPER
METABOLISM
AGE GROUPS
BLOOD PLASMA
CERULOPLASMIN
DIET
ENZYME ACTIVITY
ERYTHROCYTES
MEN
NUTRITION
NUTRITIONAL DEFICIENCY
SUPEROXIDE DISMUTASE
WOMEN
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
COMPLEXES
COPPER COMPLEXES
ELEMENTS
ENZYMES
FEMALES
GLOBULINS
GLOBULINS-ALPHA
MALES
MAMMALS
MAN
MATERIALS
METALLOPROTEINS
METALS
ORGANIC COMPOUNDS
OXIDOREDUCTASES
PRIMATES
PROTEINS
TRANSITION ELEMENT COMPLEXES
TRANSITION ELEMENTS
VERTEBRATES
550500* - Metabolism