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Title: Coronary heart disease and the zinc-to-copper ratio in human aorta and drinking water

Trace levels of zinc and copper have been determined in the aorta from individuals with known histories of coronary heart disease (experimental group) and from individuals without a history of heart disease (control group) or any condition with an alleged or known association with trace zinc and copper. Subjects for the experimental and control groups were matched in terms of age, sex, and race. The zinc-to-copper ratio in the aorta for the experimental group was found to be significantly higher than the zinc-to-copper ratio in the control group at the 90% level of confidence. The results suggest that an imbalance in the zinc-to-copper ratio is a risk factor in coronary artery disease. Data for trace elements in major water sources for different geographical areas of the US from 1962-1967 were compiled and correlations with mortality rates for heart diseases from 1969-1971 were made. The results revealed that there was an extremely high correlation between the zinc-to-copper ratio in water and mortality rates of non-white females with coronary heart disease.
Authors:
; ; ; ;
Publication Date:
OSTI Identifier:
6839898
Resource Type:
Journal Article
Resource Relation:
Journal Name: J. Tenn. Acad. Sci.; (United States); Journal Volume: 61:4
Research Org:
Benedict College, Columbia, SC
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; COPPER; BIOLOGICAL EFFECTS; CONCENTRATION RATIO; QUANTITY RATIO; TRACE AMOUNTS; MAN; INJURIES; ZINC; AORTA; CARDIOVASCULAR DISEASES; DRINKING WATER; ANIMALS; ARTERIES; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; DISEASES; ELEMENTS; HYDROGEN COMPOUNDS; MAMMALS; METALS; ORGANS; OXYGEN COMPOUNDS; PRIMATES; TRANSITION ELEMENTS; VERTEBRATES; WATER 560300* -- Chemicals Metabolism & Toxicology