Sclerosing cholangitis: cholescintigraphy with Tc-99m-labeled DISIDA
Four patients with primary sclerosing cholangitis (PCS) were examined with the hepatobiliary agent Tc-99m-labeled DISIDA (diisopropylphenylcarbamoyl iminodiacetic acid), and the results correlated with those of invasive cholangiography. Cholescintigraphy is superior to cholangiography in cases of suspected PSC where there is nonfilling of biliary radicals due to high-grade stenosis. The finding of delayed hepatic parenchymal clearance can allow estimation of the degree of obstruction of the various branches of the major bile ducts. Cholescintigraphy offers a noninvasive method of investigating patients with suspected sclerosing chloangitis, leading to earlier diagnosis. Confirmation with invasive cholangiographic procedures is recommended.
- Research Organization:
- Case Western Reserve Univ. School of Medicine and Univ. Hospitals, Cleveland, OH
- OSTI ID:
- 6834354
- Journal Information:
- Radiology; (United States), Vol. 151:1
- Country of Publication:
- United States
- Language:
- English
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