Primary tumor control after radiotherapy for carcinoma of the bronchus

Journal Article · Sun Apr 01 00:00:00 EST 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(84)90029-4· OSTI ID:6831957

Saunders, M I; Bennett, M H; Dische, S; Anderson, P J

The primary tumor control and the appearance of distant metastasis was observed closely in 62 patients entered into a randomized controlled trial of the radiosensitizing drug, misonidazole, in carcinoma of the bronchus. Sixty-one of the 62 patients are now dead; an autopsy examination was carried out in 42 (69%). Although survival was comparable to that observed in similar studies, tumor persisted or recurred at the primary site in 95% (58/61) while 39% (24/61) showed no evidence for distant metastasis. In these patients, improvement in the primary tumor control would be important in extending survival. Complications of this treatment are discussed.

• Research Organization: Mount Vernon Hospital, Northwood, England
• OSTI ID: 6831957
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:4
• Country of Publication: United States
• Language: English

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