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Title: Applied potential tomography. A new noninvasive technique for measuring gastric emptying

Abstract

Applied potential tomography is a new, noninvasive technique that yields sequential images of the resistivity of gastric contents after subjects have ingested a liquid or semisolid meal. This study validates the technique as a means of measuring gastric emptying. Experiments in vitro showed an excellent correlation between measurements of resistivity and either the square of the radius of a glass rod or the volume of water in a spherical balloon when both were placed in an oval tank containing saline. Altering the lateral position of the rod in the tank did not alter the values obtained. Images of abdominal resistivity were also directly correlated with the volume of air in a gastric balloon. Profiles of gastric emptying of liquid meals obtained using applied potential tomography were very similar to those obtained using scintigraphy or dye dilution techniques, provided that acid secretion was inhibited by cimetidine. Profiles of emptying of a mashed potato meal using applied potential tomography were also very similar to those obtained by scintigraphy. Measurements of the emptying of a liquid meal from the stomach were reproducible if acid secretion was inhibited by cimetidine. Thus, applied potential tomography is an accurate and reproducible method of measuring gastric emptyingmore » of liquids and particulate food. It is inexpensive, well tolerated, easy to use, and ideally suited for multiple studies in patients, even those who are pregnant.« less

Authors:
; ; ; ; ; ; ;
Publication Date:
Research Org.:
Univ. of Sheffield, England
OSTI Identifier:
6791060
Resource Type:
Journal Article
Journal Name:
Gastroenterology; (United States)
Additional Journal Information:
Journal Volume: 4
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; STOMACH; BIOLOGICAL FUNCTIONS; SCINTISCANNING; TOMOGRAPHY; COLLOIDS; ELECTRIC CONDUCTIVITY; ELECTRODES; GASTRIC ACID; TECHNETIUM; TIN; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISPERSIONS; ELECTRICAL PROPERTIES; ELEMENTS; FUNCTIONS; GASTROINTESTINAL TRACT; MATERIALS; METALS; ORGANS; PHYSICAL PROPERTIES; RADIOISOTOPE SCANNING; TRANSITION ELEMENTS; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550600 - Medicine

Citation Formats

Avill, R, Mangnall, Y F, Bird, N C, Brown, B H, Barber, D C, Seagar, A D, Johnson, A G, and Read, N W. Applied potential tomography. A new noninvasive technique for measuring gastric emptying. United States: N. p., 1987. Web.
Avill, R, Mangnall, Y F, Bird, N C, Brown, B H, Barber, D C, Seagar, A D, Johnson, A G, & Read, N W. Applied potential tomography. A new noninvasive technique for measuring gastric emptying. United States.
Avill, R, Mangnall, Y F, Bird, N C, Brown, B H, Barber, D C, Seagar, A D, Johnson, A G, and Read, N W. 1987. "Applied potential tomography. A new noninvasive technique for measuring gastric emptying". United States.
@article{osti_6791060,
title = {Applied potential tomography. A new noninvasive technique for measuring gastric emptying},
author = {Avill, R and Mangnall, Y F and Bird, N C and Brown, B H and Barber, D C and Seagar, A D and Johnson, A G and Read, N W},
abstractNote = {Applied potential tomography is a new, noninvasive technique that yields sequential images of the resistivity of gastric contents after subjects have ingested a liquid or semisolid meal. This study validates the technique as a means of measuring gastric emptying. Experiments in vitro showed an excellent correlation between measurements of resistivity and either the square of the radius of a glass rod or the volume of water in a spherical balloon when both were placed in an oval tank containing saline. Altering the lateral position of the rod in the tank did not alter the values obtained. Images of abdominal resistivity were also directly correlated with the volume of air in a gastric balloon. Profiles of gastric emptying of liquid meals obtained using applied potential tomography were very similar to those obtained using scintigraphy or dye dilution techniques, provided that acid secretion was inhibited by cimetidine. Profiles of emptying of a mashed potato meal using applied potential tomography were also very similar to those obtained by scintigraphy. Measurements of the emptying of a liquid meal from the stomach were reproducible if acid secretion was inhibited by cimetidine. Thus, applied potential tomography is an accurate and reproducible method of measuring gastric emptying of liquids and particulate food. It is inexpensive, well tolerated, easy to use, and ideally suited for multiple studies in patients, even those who are pregnant.},
doi = {},
url = {https://www.osti.gov/biblio/6791060}, journal = {Gastroenterology; (United States)},
number = ,
volume = 4,
place = {United States},
year = {Wed Apr 01 00:00:00 EST 1987},
month = {Wed Apr 01 00:00:00 EST 1987}
}