Value of tomographic thallium-201 imaging in patients with chest pain following coronary artery bypass grafting
To determine whether thallium-201 washout profile analysis can detect regional myocardial ischemia caused by coronary artery bypass graft occlusion or progression of disease in nonbypassed coronary arteries, 19 consecutive patients with chest pain following bypass grafting were evaluated with coronary arteriography and thallium-201 scintigraphy. Twenty of the 55 coronary artery regions were perfused by an occluded bypass graft or a significantly stenosed (greater than or equal to 70% diameter narrowing) nonbypassed coronary artery, while 35 coronary regions were perfused by patent bypass grafts or insignificantly diseased coronary arteries. The tomographic thallium-201 washout profile results correlated with the bypass graft and coronary arteriographic findings. The sensitivity of tomographic thallium-201 washout profile abnormalities for arteriographic abnormalities was 75%, while the specificity was 86%. The authors conclude that tomographic thallium-201 washout profile analysis may be very useful in the evaluation of patients with chest pain following coronary artery bypass grafting by detecting regional myocardial ischemia caused by occlusion of specific bypass grafts or progression of disease in nonbypassed coronary arteries.
- Research Organization:
- Univ. of Texas Health Science Center, San Antonio
- OSTI ID:
- 6790715
- Journal Information:
- Clin. Nucl. Med.; (United States), Vol. 2
- Country of Publication:
- United States
- Language:
- English
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CORONARIES
BIOMEDICAL RADIOGRAPHY
SCINTISCANNING
ISCHEMIA
DIAGNOSIS
THALLIUM 201
DIAGNOSTIC USES
GRAFTS
MYOCARDIUM
PATIENTS
SURGERY
TOMOGRAPHY
ARTERIES
BETA DECAY RADIOISOTOPES
BLOOD VESSELS
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CARDIOVASCULAR SYSTEM
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ISOMERIC TRANSITION ISOTOPES
ISOTOPES
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RADIOISOTOPE SCANNING
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SECONDS LIVING RADIOISOTOPES
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550601* - Medicine- Unsealed Radionuclides in Diagnostics
550602 - Medicine- External Radiation in Diagnostics- (1980-)