Two-stage triolein breath test differentiates pancreatic insufficiency from other causes of malabsorption
In 24 patients with malabsorption, (/sup 14/C)triolein breath tests were conducted before and together with the administration of pancreatic enzymes (Pancrease, Johnson and Johnson, Skillman, N.J.). Eleven patients with pancreatic insufficiency had a significant rise in peak percent dose per hour /sup 14/CO/sub 2/ excretion after Pancrease, whereas 13 patients with other causes of malabsorption had no increase in /sup 14/CO/sub 2/ excretion (2.61 +/- 0.96 vs. 0.15 +/- 0.45, p less than 0.001). The two-stage (/sup 14/C)triolein breath test appears to be an accurate and simple noninvasive test of fat malabsorption that differentiates steatorrhea secondary to pancreatic insufficiency from other causes of steatorrhea.
- Research Organization:
- Department of Medicine, University of Colorado School of Medicine, Denver
- OSTI ID:
- 6783671
- Journal Information:
- Gastroenterology; (United States), Vol. 83:1 Pt 1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
CARBON 14 COMPOUNDS
ISOTOPE APPLICATIONS
DIGESTIVE SYSTEM DISEASES
DIAGNOSIS
PANCREAS
DYNAMIC FUNCTION STUDIES
CARBON DIOXIDE
EXCRETION
FATS
METABOLISM
PATIENTS
TRIOLEIN
BODY
CARBON COMPOUNDS
CARBON OXIDES
CHALCOGENIDES
CLEARANCE
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
ESTERS
GLANDS
LABELLED COMPOUNDS
LIPIDS
OILS
ORGANIC COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
TRIGLYCERIDES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques