Thallium-201 imaging in the follow-up of differentiated thyroid carcinoma

Journal Article · Thu Sep 01 00:00:00 EDT 1988 · J. Nucl. Med.; (United States)

OSTI ID:6735378

Brendel, A J; Guyot, M; Jeandot, R; Lefort, G; Manciet, G

Since thallium-201 imaging has been reported as a potential means of follow-up of patients with differentiated thyroid carcinoma (DTC) during ongoing thyroid suppression therapy, the authors evaluated the diagnostic sensitivity of this procedure in 31 patients known to have metastases or local recurrence. Among 51 tumor sites /sup 201/TI imaging had a detection rate of 45% whereas 84% was noted for imaging with /sup 131/I administered in therapeutic doses. Thus, even though the effectiveness of the two radionuclides is not strictly comparable due to the difference in the administered doses, Thallium imaging cannot be recommended as the only modality for the follow-up of patients with DTC. Six of the eight tumor sites negative with /sup 131/I were positive with /sup 201/TI (especially metastatic cervico-mediastinal lymph nodes). So /sup 201/TI imaging may particularly be helpful in localizing metastases or recurrences in patients with a negative /sup 131/I scan and abnormal levels of serum thyroglobulin.

• Research Organization: Hopital Universitaire Pellegrin, Bordeaux (France)
• OSTI ID: 6735378
• Journal Information: J. Nucl. Med.; (United States), Vol. 29:9
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
DIAGNOSIS
EMISSION COMPUTED TOMOGRAPHY
SENSITIVITY ANALYSIS
THYROID
IODINE 131
METASTASES
PATIENTS
RADIOISOTOPE SCANNING
THALLIUM 201
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HEAVY NUCLEI
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics