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Title: In-vivo measurement of lithium in the brain and other organs

An in-vivo method of measurement of the amount of lithium present in tissue and organs of breathing animals is described. The basis for the technique is the lithium-1 neutron interaction - /sup 6/Li(n,..cap alpha..)T. The lithium is irradiated with thermal neutrons to produce tritium atoms. The tritium diffuses into the tissues and is exhaled. By measuring the amount of tritium exhaled, the lithium concentration in the irradiated zone is determined.
Authors:
; ; ; ;
Publication Date:
OSTI Identifier:
6726654
DOE Contract Number:
AC02-76CH00016
Resource Type:
Patent
Resource Relation:
Other Information: Portions are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; LITHIUM; MEASURING METHODS; TISSUE DISTRIBUTION; ALPHA PARTICLES; IN VIVO; LITHIUM 6; LITHIUM 6 TARGET; LUNG CLEARANCE; NEUTRON REACTIONS; NEUTRONS; PICKUP REACTIONS; QUANTITY RATIO; RADIOACTIVATION; TRITIUM; ALKALI METAL ISOTOPES; ALKALI METALS; BARYON REACTIONS; BARYONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHARGED PARTICLES; CLEARANCE; DIRECT REACTIONS; DISTRIBUTION; ELEMENTARY PARTICLES; ELEMENTS; EXCRETION; FERMIONS; HADRON REACTIONS; HADRONS; HYDROGEN ISOTOPES; ISOTOPES; LIGHT NUCLEI; LITHIUM ISOTOPES; METALS; NUCLEAR REACTIONS; NUCLEI; NUCLEON REACTIONS; NUCLEONS; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; RADIOISOTOPES; STABLE ISOTOPES; TARGETS; TRANSFER REACTIONS; YEARS LIVING RADIOISOTOPES 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics; 550501 -- Metabolism-- Tracer Techniques