Enhanced product formation in continuous fermentations with microbial cell recycle
Abstract
The effect of partial recycle of microbial cells on the operation of a chemostat has been investigated for two fermentations. Stable steady states with and without partial cell recycle were obtained for the conversion of d-sorbitol to L-sorbose by Gluconobacter oxydans subsp. suboxydans 1916B and for the conversion of glucose to 2-ketogluconic acid by Serratia marcescens NRRl B-486. The employment of partial cell recycle dramatically increased product formation rates for both fermentations.
- Authors:
- Publication Date:
- Research Org.:
- Chemical Research Dept, Hoffmann-La Roche Inc, Nutley, New Jersey 07110; Dept Chemical Engineering, Univ of Michigan, Ann Arbor, Michigan 48109
- OSTI Identifier:
- 6722797
- Resource Type:
- Journal Article
- Journal Name:
- Biotechnol. Bioeng.; (United States)
- Additional Journal Information:
- Journal Volume: 23:2
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 09 BIOMASS FUELS; 59 BASIC BIOLOGICAL SCIENCES; BACTERIA; CELL RECYCLE; GLUCOSE; FERMENTATION; SORBITOL; BENCH-SCALE EXPERIMENTS; CONTINUOUS CULTURE; CULTURE MEDIA; ETHANOL; GLUCONIC ACID; REACTION INTERMEDIATES; SORBOSE; ALCOHOLS; ALDEHYDES; BIOCONVERSION; CARBOHYDRATES; CARBOXYLIC ACIDS; DIURETICS; DRUGS; HEXOSES; HYDROXY ACIDS; HYDROXY COMPOUNDS; KETONES; MICROORGANISMS; MONOSACCHARIDES; ORGANIC ACIDS; ORGANIC COMPOUNDS; SACCHARIDES; 090222* - Alcohol Fuels- Preparation from Wastes or Biomass- (1976-1989); 550200 - Biochemistry; 140504 - Solar Energy Conversion- Biomass Production & Conversion- (-1989)
Citation Formats
Bull, D N, and Young, M D. Enhanced product formation in continuous fermentations with microbial cell recycle. United States: N. p., 1981.
Web. doi:10.1002/bit.260230212.
Bull, D N, & Young, M D. Enhanced product formation in continuous fermentations with microbial cell recycle. United States. https://doi.org/10.1002/bit.260230212
Bull, D N, and Young, M D. 1981.
"Enhanced product formation in continuous fermentations with microbial cell recycle". United States. https://doi.org/10.1002/bit.260230212.
@article{osti_6722797,
title = {Enhanced product formation in continuous fermentations with microbial cell recycle},
author = {Bull, D N and Young, M D},
abstractNote = {The effect of partial recycle of microbial cells on the operation of a chemostat has been investigated for two fermentations. Stable steady states with and without partial cell recycle were obtained for the conversion of d-sorbitol to L-sorbose by Gluconobacter oxydans subsp. suboxydans 1916B and for the conversion of glucose to 2-ketogluconic acid by Serratia marcescens NRRl B-486. The employment of partial cell recycle dramatically increased product formation rates for both fermentations.},
doi = {10.1002/bit.260230212},
url = {https://www.osti.gov/biblio/6722797},
journal = {Biotechnol. Bioeng.; (United States)},
number = ,
volume = 23:2,
place = {United States},
year = {Sun Feb 01 00:00:00 EST 1981},
month = {Sun Feb 01 00:00:00 EST 1981}
}
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