Preoperative irradiation in carcinoma of the pancreas. [/sup 60/Co or 46 MeV photons]

Journal Article · Sat Nov 01 00:00:00 EST 1980 · Cancer; (United States)

OSTI ID:6721025

Pilepich, M V ^[1]; Miller, H H

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1. Washington Univ., St. Louis, MO

Seventeen patients with carcinoma confined to the pancreas and the peripancreatic area received preoperative radiation therapy in an attempt to increase the resectability rate and to reduce the incidence of recurrence. The tumors were considered either unresectable or of borderline resectability. The radiation dose ranged between 4000 to 5000 rads, the majority of patients (75%) receiving 4400 to 4600 rads in 4 1/2 to 5 weeks. After a period averaging six weeks the patients were reevaluated for surgery. Eleven patients were explored and six underwent radical resection. Two patients remained disease free after five years. Pancreatic resection is feasible following a course of preoperative radiotherpy to a moderately high dose. It is suggested that the response of the primary tumor to radiotherapy be used as a criterion for selecting patients for reexploration and resection.

• OSTI ID: 6721025
• Journal Information: Cancer; (United States), Vol. 46:9
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
EVALUATION
SURGERY
BETATRONS
CARCINOMAS
COBALT 60
GAMMA RADIATION
MEV RANGE 10-100
PANCREAS
PATIENTS
SURVIVAL TIME
ACCELERATORS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COBALT ISOTOPES
CYCLIC ACCELERATORS
DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
ENERGY RANGE
GLANDS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MEV RANGE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
THERAPY
YEARS LIVING RADIOISOTOPES
550603* - Medicine- External Radiation in Therapy- (1980-)