New objective criterion for determining, noninvasively, the healing potential of an ischemic ulcer
Peripheral vascular perfusion studies using intravenously administered thallium-201 were performed on 13 patients suffering from ischemic ulcer of the lower extermities. Scintillation camera views and point counting over the lesion and adjacent region were utilized to define qualitatively and quantitatively the relative hyperemia of the lesion. The preliminary findings demonstrate that when the relative hyperemia was equal to or greater than 1.5, 100% (seven of seven) went on to heal their ulcer with conservative management. Of those without this degree of hyperemia, 83% (five of six) will require amputation. Based on this limited series, noninvasive assessment of the relative hyperemia of an ischemic ulcer using thallium-201 is a new, useful, and objective indicator of the healing potential of a so-called ischemic ulcer.
- Research Organization:
- Univ. of Southern California, Los Angeles
- OSTI ID:
- 6638899
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 22:2; Conference: 28. annual meeting of Society of Nuclear Medicine, Las Vegas, NV, USA, 16 Jun 1981
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
LEGS
SCINTISCANNING
SKIN DISEASES
DIAGNOSIS
THALLIUM 201
DIAGNOSTIC USES
ULCERS
HEALING
EVALUATION
INJECTION
ISCHEMIA
PATIENTS
PERFUSED TISSUES
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
BODY AREAS
CARDIOVASCULAR DISEASES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
INTAKE
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIMBS
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RECOVERY
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
TISSUES
USES
VASCULAR DISEASES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques