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Title: Interaction of electromagnetic fields with chondrocytes in gel culture. Final report, February-August 1989

The research accomplished during this project period focused on control experiments designed to establish whether cartilage cells from normal cartilage will continue to synthesize and accumulate normal extracellular matrix in agarose gel culture. This information is essential to properly design experiments to qualify changes in chondrocyte biosynthesis due to applied electromagnetic fields. The results suggest that both normal chondrocytes and swarm rat chondrosarcoma cells in agarose culture can continue to synthesize matrix macromolecules at a rate similar to or slightly higher than that in normal cartilage; also, that chondrocytes in agarose can successfully mediate assembly and accumulation of normal, mechanically functional extracellular matrix.
Authors:
; ;
Publication Date:
OSTI Identifier:
6612422
Report Number(s):
AD-A-223397/1/XAB
CNN: F33615-87-D-0626
Resource Type:
Technical Report
Research Org:
Massachusetts Inst. of Tech., Cambridge, MA (USA). Dept. of Electrical Engineering and Computer Science
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ANIMAL CELLS; SENSITIVITY; ELECTROMAGNETIC FIELDS; BIOLOGICAL EFFECTS; BIOSYNTHESIS; CARTILAGE; PROGRESS REPORT; RATS; TISSUE CULTURES; ANIMAL TISSUES; ANIMALS; BODY; CONNECTIVE TISSUE; DOCUMENT TYPES; MAMMALS; RODENTS; SYNTHESIS; TISSUES; VERTEBRATES 560400* -- Other Environmental Pollutant Effects