Clinical implications of anterior S-T segment depression in patients with acute inferior myocardial infarction
To assess various factors associated with anterior S-T segment depression during acute inferior myocardial infarction, 47 consecutive patients with electrocardiographic evidence of a first transmural inferior infarction were studied prospectively with radionuclide ventriculography an average of 7.3 hours (range 2.9 to 15.3) after the onset of symptoms. Thirty-nine patients (Group I) had anterior S-T depression in the initial electrocardiogram and 8 (Group II) did not have such reciprocal changes. There was no difference between the two groups in left ventricular end-diastolic or end-diastolic volume index or left ventricular ejection fraction. Stroke volume index was greater in Group I than in Group II. There were no group differences in left ventricular total or regional wall motion scores. A weak correlation existed between the quantities (mV) or inferior S-T segment elevation and reciprocal S-T depression. No relation between anterior S-T segment depression and the left ventricular end-diastolic volume index could be demonstrated; the extent of left ventricular apical and right ventricular wall motion abnormalities, both frequently associated with inferior infarction, did not correlate with the quantity of anterior S-T depression. These data show that anterior S-T segment depression occurs commonly during the early evolution of transmural inferior infarction, is not generally a marker of functionally significant anterior ischemia and cannot be used to predict left ventricular function in individual patients. Anterior S-T segment depression may be determined by reciprocal mechanisms.
- Research Organization:
- Department of Internal Medicine, Cardiology Division University of Texas, Health Science Center at Dallas
- OSTI ID:
- 6607390
- Journal Information:
- Am. J. Cardiol.; (United States), Vol. 50:3
- Country of Publication:
- United States
- Language:
- English
Similar Records
Anterior ST depression with acute transmural inferior infarction due to posterior infarction. A vectorcardiographic and scintigraphic study
Reversal of segmental hypokinesis by coronary angioplasty in patients with unstable angina, persistent T wave inversion, and left anterior descending coronary artery stenosis. Additional evidence for myocardial stunning in humans
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
MYOCARDIAL INFARCTION
DIAGNOSIS
PATHOLOGY
MYOCARDIUM
ELECTROCARDIOGRAMS
SCINTISCANNING
BLOOD CIRCULATION
CARDIOGRAPHY
COMPARATIVE EVALUATIONS
PATIENTS
VOLUME
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIAGRAMS
DISEASES
HEART
MUSCLES
ORGANS
RADIOISOTOPE SCANNING
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques