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Title: Actinic reticuloid

A 58-year-old man has his condition diagnosed as actinic reticuloid on the basis of clinical and histologic findings and phototesting data. He had clinical features resembling mycosis fungoides in light-exposed areas. Histologic findings disclosed a bandlike infiltrate with atypical mononuclear cells in the dermis and scattered atypical cells in the epidermis. Electron microscopy disclosed mononuclear cells with bizarre, convoluted nuclei, resembling cerebriform cells of Lutzner. Phototesting disclosed a diminished minimal erythemal threshold to UV-B and UV-A. Microscopic changes resembling actinic reticuloid were reproduced in this patient 24 and 72 hours after exposure to 15 minimal erythemal doses of UV-B.
Authors:
; ; ; ; ;
Publication Date:
OSTI Identifier:
6602658
Resource Type:
Journal Article
Resource Relation:
Journal Name: Arch. Dermatol.; (United States); Journal Volume: 118:9
Research Org:
Departments of Dermatology, New York University Medical Center
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; SKIN; RADIOSENSITIVITY; SKIN DISEASES; PATHOLOGY; BIOLOGICAL RADIATION EFFECTS; DIAGNOSIS; HISTOLOGY; MONOCYTES; PATIENTS; ULTRAVIOLET RADIATION; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; DISEASES; ELECTROMAGNETIC RADIATION; LEUKOCYTES; MATERIALS; ORGANS; RADIATION EFFECTS; RADIATIONS 560151* -- Radiation Effects on Animals-- Man; 550900 -- Pathology; 550300 -- Cytology