Acute radiation effects on cutaneous microvasculature: evaluation with a laser Doppler perfusion monitor

Journal Article · Tue Nov 01 00:00:00 EST 1988 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.169.2.3051122· OSTI ID:6582455

Amols, H I; Goffman, T E; Komaki, R; Cox, J D

Laser Doppler perfusion monitoring is a noninvasive technique for measuring blood flow in epidermal microvasculature that makes use of the frequency shift of light reflected from red blood cells. Measurements in patients undergoing radiation therapy show increases in blood flow of ten to 25 times baseline at doses above 50 Gy, and increases are observed with doses as low as 2 Gy. Follow-up measurements show rapid decreases in flow levels after completion of therapy, but levels remain elevated even at 1 year.

• Research Organization: Columbia Univ., New York, NY (USA)
• OSTI ID: 6582455
• Journal Information: Radiology; (United States), Vol. 169:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
EPIDERMIS
BLOOD FLOW
ERYTHROCYTES
LASERS
PATIENTS
PERFUSED TISSUES
RADIOTHERAPY
ANIMAL TISSUES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
EPITHELIUM
MATERIALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
SKIN
THERAPY
TISSUES
550600* - Medicine
550603 - Medicine- External Radiation in Therapy- (1980-)