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Title: Effect of bolus composition on esophageal transit: concise communication

Abstract

The technique of esophageal scintigraphy was developed as a sensitive, quantitative, noninvasive test of esophageal transit. Esophageal scintigraphy was performed in 40 asymptomatic normal volunteers in order to determine the effect on esophageal transit of the following: body posture (sitting vs. supine), liquid vs. solid, the solid being either a standard gelatin capsule of the size used for antibiotic capsules, or a cube of solid food such as cooked chicken liver. The results showed that liquids emptied completely from the esophagus after one swallow whether supine or sitting. Capsules or liver cubes, when ingested without water, frequently remained in the esophagus for up to two hours without the subject's having any sensation that the solid had not left the esophagus. Both capsules and liver cubes cleared the esophagus better in the upright than in the supine position. When gelatin capsules were swallowed with as little as 15 ml of water, but after a preliminary sip of water, there was complete transit in each case. The study suggests that the practice of assisting patients into a sitting position and instructing them to take a sip of water before attempting to swallow a capsule will assure better transit of the capsule evenmore » when swallowed with as little as 15 ml of water. This may reduce the incidence of esophagitis following oral antibiotics, and of esophageal erosions from aspirin-containing medications.« less

Authors:
; ; ; ;
Publication Date:
Research Org.:
Temple Univ. School of Medicine, Philadelphia, PA
OSTI Identifier:
6582387
Resource Type:
Journal Article
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 23:10
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ESOPHAGUS; DYNAMIC FUNCTION STUDIES; SCINTISCANNING; ISOMERIC NUCLEI; RADIOCOLLOIDS; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COLLOIDS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISPERSIONS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Fisher, R S, Malmud, L S, Appelgate, G, Rock, E, and Lorber, S H. Effect of bolus composition on esophageal transit: concise communication. United States: N. p., 1982. Web.
Fisher, R S, Malmud, L S, Appelgate, G, Rock, E, & Lorber, S H. Effect of bolus composition on esophageal transit: concise communication. United States.
Fisher, R S, Malmud, L S, Appelgate, G, Rock, E, and Lorber, S H. 1982. "Effect of bolus composition on esophageal transit: concise communication". United States.
@article{osti_6582387,
title = {Effect of bolus composition on esophageal transit: concise communication},
author = {Fisher, R S and Malmud, L S and Appelgate, G and Rock, E and Lorber, S H},
abstractNote = {The technique of esophageal scintigraphy was developed as a sensitive, quantitative, noninvasive test of esophageal transit. Esophageal scintigraphy was performed in 40 asymptomatic normal volunteers in order to determine the effect on esophageal transit of the following: body posture (sitting vs. supine), liquid vs. solid, the solid being either a standard gelatin capsule of the size used for antibiotic capsules, or a cube of solid food such as cooked chicken liver. The results showed that liquids emptied completely from the esophagus after one swallow whether supine or sitting. Capsules or liver cubes, when ingested without water, frequently remained in the esophagus for up to two hours without the subject's having any sensation that the solid had not left the esophagus. Both capsules and liver cubes cleared the esophagus better in the upright than in the supine position. When gelatin capsules were swallowed with as little as 15 ml of water, but after a preliminary sip of water, there was complete transit in each case. The study suggests that the practice of assisting patients into a sitting position and instructing them to take a sip of water before attempting to swallow a capsule will assure better transit of the capsule even when swallowed with as little as 15 ml of water. This may reduce the incidence of esophagitis following oral antibiotics, and of esophageal erosions from aspirin-containing medications.},
doi = {},
url = {https://www.osti.gov/biblio/6582387}, journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 23:10,
place = {United States},
year = {Fri Oct 01 00:00:00 EDT 1982},
month = {Fri Oct 01 00:00:00 EDT 1982}
}