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Title: Radioisotope therapy of cystic craniopharyngeomas

Abstract

Eighteen patients suffering from cystic craniopharyngeoma were treated with intracavitary irradiation. The beta-emitting radioisotope /sup 90/y (2.25 MeV) was instilled into the cyst following stereotactic puncture of the space-occupying lesion. The surgical approach was planned using angiograms and reconstructed transmission computer tomography (TCT) coronal and saggital sections. Therapy was devised to deliver 20,000 rad to the cyst's wall. Eleven patients received follow-up TCT examinations after four months. Eight of 11 patients had a significant volume decrease in the craniopharyngeoma cyst. In two patients, the cystic volume remained unchanged; one had progression of disease. It is concluded that the intracavitary treatment of cystic craniopharyngeoma will result in a reduction of the size of the space-occupying lesion.

Authors:
; ; ; ; ; ;
Publication Date:
Research Org.:
Univ. of Heidelberg, West Germany
OSTI Identifier:
6565566
Resource Type:
Journal Article
Journal Name:
Int. J. Radiat. Oncol., Biol. Phys.; (United States)
Additional Journal Information:
Journal Volume: 8:9
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOMEDICAL RADIOGRAPHY; DIAGNOSTIC USES; COMPUTERIZED TOMOGRAPHY; RADIOTHERAPY; RADIATION SOURCE IMPLANTS; BLOOD VESSELS; BRAIN; NEOPLASMS; SILICATES; YTTRIUM 90; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; HOURS LIVING RADIOISOTOPES; IMPLANTS; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; OXYGEN COMPOUNDS; RADIATION SOURCES; RADIOISOTOPES; RADIOLOGY; SILICON COMPOUNDS; THERAPY; TOMOGRAPHY; USES; YTTRIUM ISOTOPES; 550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-); 550602 - Medicine- External Radiation in Diagnostics- (1980-)

Citation Formats

Strauss, L, Sturm, V, Georgi, P, Schlegel, W, Ostertag, H, Clorius, J H, and Van Kaick, G. Radioisotope therapy of cystic craniopharyngeomas. United States: N. p., 1982. Web. doi:10.1016/0360-3016(82)90620-4.
Strauss, L, Sturm, V, Georgi, P, Schlegel, W, Ostertag, H, Clorius, J H, & Van Kaick, G. Radioisotope therapy of cystic craniopharyngeomas. United States. https://doi.org/10.1016/0360-3016(82)90620-4
Strauss, L, Sturm, V, Georgi, P, Schlegel, W, Ostertag, H, Clorius, J H, and Van Kaick, G. 1982. "Radioisotope therapy of cystic craniopharyngeomas". United States. https://doi.org/10.1016/0360-3016(82)90620-4.
@article{osti_6565566,
title = {Radioisotope therapy of cystic craniopharyngeomas},
author = {Strauss, L and Sturm, V and Georgi, P and Schlegel, W and Ostertag, H and Clorius, J H and Van Kaick, G},
abstractNote = {Eighteen patients suffering from cystic craniopharyngeoma were treated with intracavitary irradiation. The beta-emitting radioisotope /sup 90/y (2.25 MeV) was instilled into the cyst following stereotactic puncture of the space-occupying lesion. The surgical approach was planned using angiograms and reconstructed transmission computer tomography (TCT) coronal and saggital sections. Therapy was devised to deliver 20,000 rad to the cyst's wall. Eleven patients received follow-up TCT examinations after four months. Eight of 11 patients had a significant volume decrease in the craniopharyngeoma cyst. In two patients, the cystic volume remained unchanged; one had progression of disease. It is concluded that the intracavitary treatment of cystic craniopharyngeoma will result in a reduction of the size of the space-occupying lesion.},
doi = {10.1016/0360-3016(82)90620-4},
url = {https://www.osti.gov/biblio/6565566}, journal = {Int. J. Radiat. Oncol., Biol. Phys.; (United States)},
number = ,
volume = 8:9,
place = {United States},
year = {Wed Sep 01 00:00:00 EDT 1982},
month = {Wed Sep 01 00:00:00 EDT 1982}
}