Relationship between external and internal parameters of exposure to manganese in workers from a manganese oxide and salt producing plant
In a plant producing manganese (Mn) oxides and salts, 11 different workplaces were identified. The current exposure to airborne Mn (total dust, personal sampling, n = 80) varied from 0.07 to 8.61 mg/m3. The geometric mean and median values amounted approximately to 1 mg/m3 and the 95th percentile was 3.30 mg/m3. The concentration of Mn in blood (Mn-B) in a group of 141 Mn-exposed male workers ranged from 0.10-3.59 micrograms/100 ml compared to 0.04-1.31 micrograms/100 ml in a group of 104 control subjects. The ranges of the concentrations of Mn in urine (Mn-U) were 0.06-140.6 and 0.01-5.04 micrograms/g creatinine for the exposed and control groups, respectively. The average level of Mn-B in the Mn group was more than twice as high as in the control group (arithmetic mean, 1.36 vs 0.57 microgram/100 ml) and that of Mn-U was ten times higher in the Mn group (geometric mean, 1.56 vs 0.15 microgram/g creatinine). The Mn-B level did not change significantly after 8 h of Mn exposure, whereas the Mn-U level dropped rapidly when exposure ceased (half-life less than 30 h). On an individual basis, neither Mn-B nor Mn-U correlated with the current levels of Mn-air or duration of Mn exposure. There was also no relationship between Mn-B and Mn-U. On a group basis, there was no correlation between the mean Mn-B levels and the current levels of Mn-air at each workplace.
- Research Organization:
- Univ. of Louvain, Brussels, Belgium
- OSTI ID:
- 6496506
- Journal Information:
- Am. J. Ind. Med.; (United States), Vol. 3
- Country of Publication:
- United States
- Language:
- English
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54 ENVIRONMENTAL SCIENCES
MANGANESE
ECOLOGICAL CONCENTRATION
UPTAKE
BLOOD
INDOOR AIR POLLUTION
OCCUPATIONAL EXPOSURE
PERSONNEL
URINE
AIR POLLUTION
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
ELEMENTS
MATERIALS
METALS
POLLUTION
TRANSITION ELEMENTS
WASTES
560300* - Chemicals Metabolism & Toxicology
500200 - Environment
Atmospheric- Chemicals Monitoring & Transport- (-1989)